物质信息

ID:719757

N,N-二甲基甘氨酸

名称和标识
IUPAC传统名
dimethylglycine
IUPAC标准名
2-(dimethylamino)acetic acid
别名
N,N-DimethylglycineN,N-二甲基甘氨酸Dimethylaminoacetic acid
数据登录号
CAS号
默克索引号
化合物性质
安全信息
GHS危险声明
H302
GHS警示性声明
P264-P270-P301+P312-P330-P501A
GHS危险品标识
GHS07
急性毒性(口服,皮肤接触,吸入),类别4
皮肤刺激,类别2
眼刺激,类别2
皮肤过敏,类别1
特定目标器官毒性 -一次接触,类别3
保存注意事项
Hygroscopic
TSCA收录
RTECS编号
MB9865000
产品相关信息
纯度
98+%
理化性质
熔点
179-183°C
描述信息
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分子图谱
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参考文献
• Additive which promotes the Heck coupling reaction of unactivated aryl chlorides with alkenes, catalyzed by Pd(II) in the presence of Tetraphenylphosphonium chloride, A10575: Angew. Chem. Int. Ed., 37, 481 (1998). The combination with Bis(benzonitrile)dichloropalladum constitutes a highly active phosphine-free catalyst system for Heck reactions of aryl bromides: Tetrahedron Lett., 39, 8449 (1998); see also: Tetrahedron Lett., 39, 8449 (1998). Promotes the copper(I)-catalyzed Ullmann-type coupling of aryl bromides and iodides with amines: Org. Lett., 5, 2453 (2003), and phenols: Org. Lett., 5, 3799 (2003), to give substituted anilines and diaryl ethers, respectively. Aryl iodides can also be coupled with aliphatic alcohols to give aryl alkyl ethers: Synlett, 243 (2007). In combinatiion with CuI, vinyl halides with phenols give aryl vinyl ethers: Synlett, 1767 (2005).