物质信息
ID:716611
名称和标识
IUPAC传统名
formicin
IUPAC标准名
N-(hydroxymethyl)acetamide
别名
N-(Hydroxymethyl)acetamideN-(羟甲基)乙酰胺AcetamidomethanolFormicin
化合物性质
安全信息
RTECS编号
AC3610000
保存注意事项
Hygroscopic
TSCA收录
否
理化性质
熔点
47-52°C
密度
1.14
产品相关信息
纯度
98%
描述信息
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分子图谱
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参考文献
• Thiol blocking group for cysteine residues in peptide synthesis: Tetrahedron Lett., 3057 (1968); J. Am. Chem. Soc., 91, 502 (1969); 94, 5456 (1972); Helv. Chim. Acta, 54, 927 (1971); Org. Synth. Coll., 6, 5 (1988). Cleavage can be effected with Hg(OAc)2 under mild conditions, or by treatment with iodine with concomitant oxidation to the cystine derivative. For peptide reagents, see Appendix 6.
• Used for the introduction of the acetamidomethyl group into the aromatic nucleus by electrophilic substitution. For reviews of amidomethylation, see: Org. React., 14, 52 (1965); Synthesis, 49, (1970); 85, 181 (1984).