物质信息
ID:715842
名称和标识
IUPAC标准名
ol
IUPAC传统名
tyrosine(.)
别名
2,2,6,6-Tetramethyl-1-piperidinyloxy, free radical2,2,6,6-四甲基哌啶氧化物, 自由基TEMPO, free radical
化合物性质
安全信息
联合国危险货物等级
8
GHS警示性声明
P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501A
安全公开号
26-36/37/39-45-60
联合国危险货物包装类别(PG)
III
欧盟危险性物质标志
腐蚀性 (C)危险公开号
34
联合国危险货物编号
UN3263
GHS危险声明
H314-H318
GHS危险品标识
腐蚀金属，类别1
腐蚀皮肤，类别1A，1B，1C
严重眼损伤，类别1
RTECS编号
TN8991900
TSCA收录
是
理化性质
沸点
193°C dec.
闪点
67°C(152°F)
熔点
31-40°C
产品相关信息
纯度
98+%
描述信息
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分子图谱
暂无数据
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参考文献
• The addition of quaternary salts to the reaction mixture permits further oxidation of aldehydes to acids. Selective oxidation of a primary OH to an aldehyde can be achieved in the presence of a secondary OH: J. Org. Chem., 54, 2970 (1989); Tetrahedron Lett., 31, 2177 (1990). The oxidation can also be performed using NCS under phase-transfer conditions: J. Org. Chem., 61, 7452 (1996), with Iodosobenzene diacetate, B24531: J. Org. Chem., 62, 6974 (1997), or Trichloroisocyanuric acid, B23906: Org. Lett., 3, 3041 (2001).
• Cf also 4-Hydroxy-TEMPO, A12497, and 4-Acetamido-TEMPO, B23456.
• For a review of the use of stable nitroxyl radicals for the oxidation of primary and secondary alcohols, see: Synthesis, 1153 (1996).
• In the presence of a catalytic amount of KBr, catalyzes the selective oxidation of primary and secondary alcohols to aldehydes and ketones by buffered NaOCl: J. Org. Chem., 50, 4888 (1985); 52, 2559 (1987); Org. Synth. Coll., 8, 367 (1993). High yields of aldehydes can also be obtained under mild, phase-transfer conditions with Oxone.: Org. Lett., 2, 1173 (2000). In the presence of CuCl, aerobic oxidation of alcohols to aldehydes and ketones has been accomplished in the ionic liquid 1-n-Butyl-3-methylimidazolium hexafluorophosphate, L19086: Org. Lett., 4, 1507 (2002). With NaOCl, ɑ-amino or ɑ-alkoxy alcohols have also been oxidized to the aldehydes: Tetrahedron Lett., 33, 5029 (1992). The use of I2 as cooxidant is useful for sensitive substrates: Org. Lett., 5, 235 (2003).
• For brief features on TEMPO and related reagents, see: Synlett, 563 (2001); 1757 (2003); 657 (2006). For reviews on nitroxide radicals, see: Synthesis, 190, 401 (1971); Chem. Rev., 78, 37 (1978); J. Sci. Ind. Res., 54, 623 (1995).