物质信息

ID:682

名称和标识
别名
HalazepamHalazepamum [INN-Latin]
IUPAC传统名
halazepam
IUPAC标准名
7-chloro-5-phenyl-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one
商标名
PaxipamPacinone
数据登录号
PubChem CID
PubChem SID
化合物性质
理化性质
疏水性(logP)
4.3
描述信息
Drug Groups
illicit; approved
Description
Halazepam is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is a trifluoromethyl derivative of nordazepam. While its structure may be similar to chlordiazepoxide and diazepam, it has both less toxicity and less tendency to cause paradoxical hostility and aggression than either of them. [Wikipedia]
Indication
Used to relieve anxiety, nervousness, and tension associated with anxiety disorders.
Affected Organisms
Humans and other mammals
Biotransformation
Hepatic.
References
• Fann WE, Pitts WM, Wheless JC: Pharmacology, efficacy, and adverse effects of halazepam, a new benzodiazepine. Pharmacotherapy. 1982 Mar-Apr;2(2):72-9. [Pubmed]
External Links
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参考文献
• Fann WE, Pitts WM, Wheless JC: Pharmacology, efficacy, and adverse effects of halazepam, a new benzodiazepine. Pharmacotherapy. 1982 Mar-Apr;2(2):72-9. Pubmed