物质信息

ID:678

名称和标识
IUPAC传统名
tolazoline
IUPAC标准名
2-benzyl-4,5-dihydro-1H-imidazole
商标名
PriscolineImidalinPeripherinePhenylmethylimidazolineVasimidTolazolinVasodilBenzazolineBenzolinBenzylimidazolineDivascolDilatol AsiKasimidLambrilOlitensolPriscolArtonilBenzidazolImidalinePrefaxilVasodilatan
别名
Tolazoline
数据登录号
CAS号
PubChem CID
PubChem SID
化合物性质
理化性质
疏水性(logP)
1.5
溶解度
373 mg/L
描述信息
Drug Groups
approved
Description
A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn. [PubChem]
Indication
For the treatment of pulmonary artery anomalies
Pharmacology
Tolazoline is a pulmonary vasodilator indicated used to decrease pulmonary vascular resistance (PVR) in persistent pulmonary hypertension of the newborn (PPHN).
Affected Organisms
Humans and other mammals
External Links
分子图谱
暂无数据
点击上传数据
参考文献
暂无数据
点击上传数据