物质信息
ID:6574
名称和标识
商标名
HistostabAntastenAntastanAntistinAntihistal
IUPAC标准名
N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline
别名
PhenazolineAntazolinePhenazolin
IUPAC传统名
antazoline
数据登录号
CAS号
化合物性质
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描述信息
Drug Groups
approved
Description
Antazoline is a 1st generation antihistamine that also anticholinergic properties used to relieve nasal congestion and in eye drops, usually in combination with naphazoline, to relieve the symptoms of allergic conjunctivitis.
Indication
Used to relieve nasal congestion and in eye drops, usually in combination with naphazoline, to relieve the symptoms of allergic conjunctivitis.
Pharmacology
Antazoline is a histamine H1 receptor antagonist. It selectively bind to but does not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
Affected Organisms
Humans and other mammals
References
•
Figus M, Fogagnolo P, Lazzeri S, Capizzi F, Romagnoli M, Canovetti A, Iester M, Ferreras A, Rossetti L, Nardi M: Treatment of allergic conjunctivitis: results of a 1-month, single-masked randomized study. Eur J Ophthalmol. 2010 Sep-Oct;20(5):811-8.
[Pubmed]
External Links
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参考文献
• Figus M, Fogagnolo P, Lazzeri S, Capizzi F, Romagnoli M, Canovetti A, Iester M, Ferreras A, Rossetti L, Nardi M: Treatment of allergic conjunctivitis: results of a 1-month, single-masked randomized study. Eur J Ophthalmol. 2010 Sep-Oct;20(5):811-8. Pubmed