Drug Groups

approved

Description

An alpha-2 selective adrenergic agonist used as an antihypertensive agent. [PubChem]

Indication

For management of High blood pressure

Pharmacology

Guanabenz, a centrally acting α-2 adrenergic agonist, is indicated for treatment of hypertension.

Toxicity

Excessive contraction of the pupils, irritability, low blood pressure, sleepiness, slow heartbeat, sluggishness

Affected Organisms

Biotransformation

Hepatic

Absorption

Approximately 75% absorbed from gastrointestinal tract

Half Life

6 hours.

Protein Binding

90%

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