物质信息

ID:4521

名称和标识
别名
FluspirileneFluspirileno [inn-spanish]Fluspirilenum [inn-latin]
IUPAC传统名
imap
商标名
ImapRedeptinLopac-F-100
IUPAC标准名
8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
数据登录号
CAS号
PubChem SID
PubChem CID
化合物性质
理化性质
溶解度
0.01 mg/mL at 25 oC [MERCK INDEX (1996)]
疏水性(logP)
5.86 [HANSCH,C ET AL. (1995)]
描述信息
Drug Groups
approved
Description
A long-acting injectable antipsychotic agent used for chronic schizophrenia.
Indication
Used for the treatment of schizophrenia.
Pharmacology
Fluspirilene is a relatively long-acting injectable depot antipsychotic drug used for schizophrenia. Fluspirilene does not differ greatly from other depot antipsychotics (fluphenazine decanoate, fluphenazine enathate, perphenazine onanthat, pipotiazine undecylenate) with respect to treatment efficacy, response or tolerability. Outcomes suggest that fluspirilene does not differ significantly from oral antipsychotics or in different weekly regimens, although much cannot be inferred because of the shortage of trials.
Affected Organisms
Humans and other mammals
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