物质信息

ID:4499

名称和标识
别名
N-benzyl-beta-(isonicotinylhydrazino)propionamideNialamidum [inn-latin]2-[2-(Benzylcarbamoyl)ethyl]hydrazide isonicotinic acidBEIHN-(2-(Benzylcarbamyl)ethylamino)isonicotinamideN-benzyl-beta-(isonicotinoylhydrazine)propionamideN-Benzyl-3-(2-isonicotinoylhydrazino)propanamideNialamida [inn-spanish]Pyridine-4-carboxylic 2-[2-(benzylcarbamoyl)ethyl]hydrazide2-(2-(Benzylcarbamyl)ethyl)hydrazide isonicotinic acidIsonicotinic acid 2-((2-benzylcarbamoyl)ethyl)hydrazideIsonicotinic acid, 2-[2-(benzylcarbamoyl)ethyl]hydrazideIsonicotinic acid, 2-[2-(benzylcarbamoylethyl]hydrazideIsonicotinic acid, {2-[2-(benzylcarbamoyl)ethyl]hydrazide}Isonicotinic acid, {2-[2-(benzylcarbamoylethyl]hydrazide}1-[2-(Benzylcarbamoyl)ethyl]-2-isonicotinoylhydrazineLopac-N-13921-(2-(Benzylcarbamoyl)ethyl)-2-isonicotinoylhydrazine2-(2-(Benzylcarbamoyl)ethyl)hydrazide, isonicotinic acidIsonicotinic acid, 2-(2-(benzylcarbamoyl)ethyl)hydrazideIsonicotinic acid, 2-[2- (benzylcarbamoyl)ethyl]hydrazide2-(2-(Benzylcarbamoyl)ethyl)hydrazide isonicotinic acidIsonicitinic acid 2-[(2-benzylcarbamoyl)ethyl]hydrazideN-isonicotinoyl-n'(beta-n-benzylcarboxamidoethyl)hydrazineN-isonicotinyl hydrazideNialamide
IUPAC传统名
nialamide
商标名
NuredalEsprilNiamideNovazidNiamidNiamidalNyazinPsicodistenSurgexDelmoneurinaMygalIsalizinaNiazinNyezinNF-xIIINialamidNiaquitil
IUPAC标准名
N-benzyl-3-(pyridin-4-ylformohydrazido)propanamide
数据登录号
CAS号
51-12-7
PubChem CID
4472
PubChem SID
46506047
化合物性质
理化性质
疏水性(logP)
0.87 [HANSCH,C ET AL. (1995)]
描述信息
Drug Groups
withdrawn
Description
Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
Affected Organisms
Humans and other mammals
References
• Benady DR, Clein LJ, Pare CM: Intramuscular nialamide in intractable depression. Dis Nerv Syst. 1965 Dec;26(12):792-4. [Pubmed]
• OULES J, CAZABON: [TREATMENT OF DEPRESSIVE STATES WITH INTRAVENOUS NIAMIDE.] Toulouse Med. 1964 Dec;65:1298-302. [Pubmed]
• VAISBERG M, McGAHEE CL, RADINGER N, SAUNDERS JC: Nialamide for the treatment of anergy and depression. Dis Nerv Syst. 1959 Aug;20(Suppl):22-5. [Pubmed]
External Links
• [Wikipedia]
分子图谱
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参考文献
• OULES J, CAZABON: [TREATMENT OF DEPRESSIVE STATES WITH INTRAVENOUS NIAMIDE.] Toulouse Med. 1964 Dec;65:1298-302. Pubmed
• VAISBERG M, McGAHEE CL, RADINGER N, SAUNDERS JC: Nialamide for the treatment of anergy and depression. Dis Nerv Syst. 1959 Aug;20(Suppl):22-5. Pubmed
• Benady DR, Clein LJ, Pare CM: Intramuscular nialamide in intractable depression. Dis Nerv Syst. 1965 Dec;26(12):792-4. Pubmed
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