物质信息
ID:449858
名称和标识
别名
GalvusLAF237ZomelisVildagliptin
IUPAC标准名
(2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}pyrrolidine-2-carbonitrile
IUPAC传统名
(2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}pyrrolidine-2-carbonitrile
数据登录号
CAS号
化合物性质
产品相关信息
应用领域
Anti-hyperglycemic agent
药理学性质
生物活性机理
Dipeptidyl peptidase-4 (DPP-4) inhibitor
描述信息
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分子图谱
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参考文献
• for their degradation in human serum". European journal of biochemistry / FEBS 214 (3): 829?5.
• 2. Mentlein, R; Gallwitz, B; Schmidt, WE (1993). "Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible
• in type 2 diabetes". The Journal of clinical endocrinology and metabolism 89 (5): 2078?4.
• 1. Ahre'n, B; Landin-Olsson, M; Jansson, PA; Svensson, M; Holmes, D; Schweizer, A (2004). "Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels, and reduces glucagon levels