物质信息

ID:449847

Dobutamine hydrochloride

名称和标识
IUPAC标准名
4-(2-{[(2S)-4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol
别名
InofrexDobutrexDobutamine hydrochloride
IUPAC传统名
4-(2-{[(2S)-4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol
数据登录号
化合物性质
产品相关信息
应用领域
Used in the treatment of heart failure and cardiogenic shock
Sympathomimetic drug
药理学性质
生物活性机理
Stimulation of beta1 receptors of the sympathetic nervous system
描述信息
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分子图谱
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参考文献
• Rang HP, Dale MM, Ritter JM, Flower RJ. Rang and Dale's Pharmacology.
• Parker K, Brunton L, Goodman LS, Blumenthal D, Buxton I (2008). Goodman & Gilman's manual of pharmacology and therapeutics. McGraw-Hill Medical. pp. 159. ISBN 0-07-144343-6.
• Shen, Howard (2008). Illustrated Pharmacology Memory Cards: PharMnemonics. Minireview. p. 6. ISBN 1-59541-101-1.
• Am. J. Respir. Crit. Care Med. 156 (2 Pt 1): 438?4. PMID 9279221
• Tuttle RR, Mills J (January 1975). "Dobutamine: development of a new catecholamine to selectively increase cardiac contractility". Circ Res 36 (1): 185?6. PMID 234805.
• Tibayan FA, Chesnutt AN, Folkesson HG, Eandi J, Matthay MA (1997). "Dobutamine increases alveolar liquid clearance in ventilated rats by beta-2 receptor stimulation".