物质信息
ID:449803
名称和标识
IUPAC标准名
benzyl N-{[(2R,4S,7R)-6,11-dimethyl-6,11-diazatetracyclo[7.6.1.02,7.012,16]hexadeca-1(16),9,12,14-tetraen-4-yl]methyl}carbamate
别名
MetergolineMethergolineLiserdolAl-Migren
IUPAC传统名
benzyl N-{[(2R,4S,7R)-6,11-dimethyl-6,11-diazatetracyclo[7.6.1.02,7.012,16]hexadeca-1(16),9,12,14-tetraen-4-yl]methyl}carbamate
数据登录号
CAS号
化合物性质
药理学性质
生物活性机理
5-HT2 antagonist
Dopamine agonist
Serotonin receptor antagonist
Has moderate affinity for 5-HT6 and high affinity for 5-HT7
5-HT1 antagonist and 5-HT1D ligand
产品相关信息
应用领域
Migraine disorgers therapy
Analgesic
Antipyretic
描述信息
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分子图谱
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参考文献
• Bagdy et al (1992) Pharmacological characterization of serotonin receptor subtypes involved in vasopressin and plasma renin activity responses to serotonin agonists. Eur.J.Pharmacol. 210 285.