物质信息
ID:449768
名称和标识
IUPAC标准名
4-amino-N-(pyrimidin-2-yl)benzene-1-sulfonamide
别名
SulfadiazineSulfadiazineTriple SulfasTriple SulfoidNeotrizineSulfaloidTerfonylLantrisulTriple SulfaSulfonamides DuplexSulfose
IUPAC传统名
4-amino-N-(pyrimidin-2-yl)benzene-1-sulfonamide
数据登录号
CAS号
化合物性质
药理学性质
生物活性机理
Folate synthesis inhibitor
Folate antagonist
Restrict folate synthesis through competitive antagonism of PABA
产品相关信息
应用领域
Used in some countries for control of bacterial disease in farmed fish
Antibacterial agent
描述信息
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分子图谱
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参考文献
• Stober, H. et al., Anal. Profiles Drug Subst., 1982, 11, 523; 1984, 13, 553, (rev, synth, pharmacol, anal)
• Sigel, C.W., Handb. Exp. Pharmacol., 1983, 64, 163, (rev, metab)
• Bult, A., Pharm. Weekbl., Sci. Ed., 1983, 5, 77, (cmr, tautom)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 1477
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 201; 206
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 392A, (nmr)
• Kracmar, J. et al., Pharmazie, 1975, 30; 447, (uv)
• Bass, A.D., Drill's Pharmacol. Med., 4th edn., McGraw-Hill, New York, 1971, 1657, (rev, pharmacol)
• Kokila, M.K. et al., Acta Cryst. C, 1995, 51, 333, (cryst struct)
• Roblin, R.O., J.A.C.S., 1940, 62, 2002, (synth)
• Gehring, T.A. et al., J. Agric. Food Chem., 1996, 44, 3164-3169, (anal)
• Cai, E., CA, 1982, 96, 57702, (synth)
• Chang, C.J. et al., J. Med. Chem., 1975, 18, 505, (pmr)
• Joshi, V.V. et al., Indian J. Phys., A, 1983, 57, 79, (cryst struct)
• Przybylski, M. et al., Adv. Mass Spectrom. Biochem. Med., Proc. Int. Symp. Mass Spectrom. Biochem. Med. 2nd, 3rd, 1976, 1, 309, (ms)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, MRM250; SNI425; PPP500