物质信息
ID:449752
名称和标识
IUPAC标准名
5-carboxy-2-methylpyrazin-1-ium-1-olate
别名
Acipimox
IUPAC传统名
5-carboxy-2-methylpyrazin-1-ium-1-olate
数据登录号
CAS号
化合物性质
药理学性质
生物活性机理
Reductor of plasma VLDL levels
Appears to reduce apoprotein-B-synthesis
Reductor of Apoprotein-B levels
Reported adipose-tissue lipolysis-inhibitor
产品相关信息
应用领域
Antihyperlipidaemic agent
描述信息
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分子图谱
暂无数据
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参考文献
• Aktories, K. et al., Arzneim.-Forsch., 1983, 33, 1525, (activity)
• Borsotti, G.P. et al., Synthesis, 1990, 207, (synth, pmr, ms)
• Felder, E. et al., Chem. Ber., 1967, 100, 555, (synth)
• Musatti, L. et al., J. Int. Med. Res., 1981, 9, 381, (pharmacol)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 983
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 409A, (nmr)
• Pitr, D. et al., Chem. Ber., 1966, 99, 9745
• Orsini, G. et al., Pharmacol. Res. Commun., 1985, 17, 927, (tox)
• Iovel, I. et al., Org. Prep. Proced. Int., 1991, 23, 188, (synth)