物质信息
ID:449751
名称和标识
IUPAC标准名
(2S)-3-methyl-2-[N-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)pentanamido]butanoic acid
别名
ValsartanValtan
IUPAC传统名
(2S)-3-methyl-2-[N-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)pentanamido]butanoic acid
数据登录号
CAS号
化合物性质
药理学性质
生物活性机理
Angiotensin 2 receptor antagonist
产品相关信息
应用领域
Antihypertensive agent
描述信息
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分子图谱
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参考文献
• Buhlmayer, P. et al., Bioorg. Med. Chem. Lett., 1994, 4, 29, (synth)
• Langley, H.D. et al., Drugs, 1999, 57, 751-755, (rev)
• Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 960
• Criscione, L. et al., Br. J. Pharmacol., 1993, 110, 761, (pharmacol)
• Wood, J.M. et al., Hypertension (Dallas), 1993, 21, 1056, (pharmacol)
• Eur. Pat., 1991, Ciba-Geigy, 443 983; CA, 116, 151772t, (synth, pharmacol)
• Markham, A. et al., Drugs, 1997, 54, 299-311, (rev)