物质信息
ID:449647
名称和标识
IUPAC标准名
2-[2-hydroxy-5-(prop-2-en-1-yl)phenyl]-4-(prop-2-en-1-yl)phenol
别名
Magnolol
IUPAC传统名
2-[2-hydroxy-5-(prop-2-en-1-yl)phenyl]-4-(prop-2-en-1-yl)phenol
数据登录号
CAS号
化合物性质
药理学性质
生物活性机理
CNS depressant with serotonergic activity
Reported from in-vitro study in rat aorta to produce relaxation of vascular smooth-muscle mediated by: release of endothelium derived relaxant factor
Inhibition of calcium influx through voltage gated channels
产品相关信息
应用领域
Antibacterial, antifungal agent
Antiplatelet agent
Sedative
Relaxant
Shows antiinflammatory and analgesic effects
生物来源
Constit. of Sassafras randaiense and Magnolia spp.
描述信息
暂无数据
点击上传数据
分子图谱
暂无数据
点击上传数据
参考文献
• El-Feraly, F.S. et al., J. Nat. Prod., 1983, 46, 493
• Hattori, M. et al., Chem. Pharm. Bull., 1984, 32, 5010; 1986, 34, 158, (metab)
• Ho, T.I. et al., CA, 1986, 105, 152803, (synth)
• Watanabe, K. et al., Planta Med., 1983, 49, 103, (isol, pharmacol)
• Teng, C.-M. et al., Thromb. Res., 1988, 50, 757, (pharmacol)
• Wang, Y. et al., J. Chin. Chem. Soc. (Peking), 1982, 30, 215, (cryst struct)
• Kim, Y.-K. et al., Planta Med., 1996, 65, 291-292, (activity)
• Clark, A.M. et al., J. Pharm. Sci., 1981, 70, 951, (props)
• Wang, J.-P. et al., Naunyn-Schmiedeberg's Arch. Pharmacol., 1992, 346, 707, (pharmacol)
• Agharahimi, M.R. et al., J.O.C., 1995, 60, 1856, (synth, ir, pmr, cmr, ms)
• Runeberg, J. et al., Acta Chem. Scand., 1957, 11, 1060; 1958, 12, 188
• Tsai, T.-H. et al., Neurosci. Lett., 1995, 186, 49, (pharmacol)
• Tsai, T.-H. et al., Drug Metab. Dispos., 1994, 22, 518, (hplc, pharmacokinet)