物质信息
ID:449643
名称和标识
别名
Prednisolone hemisuccinate
IUPAC标准名
4-{2-[(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-14-yl]-2-oxoethoxy}-4-oxobutanoic acid
IUPAC传统名
4-{2-[(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-14-yl]-2-oxoethoxy}-4-oxobutanoic acid
数据登录号
CAS号
化合物性质
药理学性质
生物活性机理
Gluconeogenesis promoter
Glucocorticoid
ACTH secretion inhibitor
Phosphorus mobilizer
Calcium mobilizer
Glycogen deposition inhibitor
ACTH antagonist
产品相关信息
应用领域
Antiallergic agent
Immunosuppressive
Antiinflammatory,
描述信息
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分子图谱
暂无数据
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参考文献
• Smith, L.L. et al., J.O.C., 1958, 23, 960, (spectra)
• McAleer, W.J. et al., J.O.C., 1958, 23, 508, (synth)
• Herzog, H.L. et al., Tetrahedron, 1962, 18, 581, (synth, ir, pmr, uv)
• Gladiali, S. et al., Chem. Ind. (London), 1977, 982, (synth)
• Martindale, The Extra Pharmacopoeia, 28th/29th edn., Pharmaceutical Press, 1982, 12869
• Pechet, M.M. et al., J. Colloid Sci., 1959, 38, 681, (pharmacol)