物质信息
ID:449623
名称和标识
IUPAC标准名
(1S,2R,10R,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
别名
Cortodoxone cortifen
IUPAC传统名
(1S,2R,10R,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
数据登录号
CAS号
化合物性质
产品相关信息
应用领域
Immunosuppressive
Antiinflammatory drug
生物来源
Found in the blood and urine of humans and other mammals
药理学性质
生物活性机理
ACTH antagonist
Phosphorus mobilizer
Glucocorticoid
ACTH secretion inhibitor
Calcium mobilizer
Gluconeogenesis promoter
Glycogen deposition inhibitor
描述信息
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分子图谱
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参考文献
• Aldrich Library of FT-IR Spectra, 1st edn. , 1985, 2 , 1054C, (ir)
• Gallagher, T.F. et al. , J.A.C.S. , 1949, 71 , 3262, (synth)
• Julian, P.L. et al. , J.A.C.S. , 1950, 72 , 5145, (synth)
• Boar, R.B. , J.C.S. Perkin 1 , 1975, 1275, (pmr)
• Numazawa, M. et al. , J.O.C. , 1985, 50 , 81, (synth)
• Gonzalez, M.D. et al. , Org. Magn. Reson. , 1984, 22 , 586, (cmr)
• Reichstein, T. et al. , Helv. Chim. Acta , 1938, 21 , 1197, (isol, synth)
• Tseikinskii, V.M. et al. , Bioorg. Khim. , 1979, 5 , 1537, (cryst struct)
• Dupont, L. et al. , Acta Cryst. , 1973, 29 , 205, (cryst struct)
• Aldrich Library of 13C and 1H FT NMR Spectra , 1992, 3 , 584B, (nmr)
• Smit, A. et al. , Rec. Trav. Chim. (J. R. Neth. Chem. Soc.) , 1966, 85, 731, (synth)