物质信息
ID:449608
名称和标识
IUPAC标准名
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
别名
MelatoninN -Acetyl-5-methoxytryptamineN -[2-(5-Methoxy-1 H -indol-3-yl)ethyl]acetamide
IUPAC传统名
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
数据登录号
CAS号
化合物性质
产品相关信息
应用领域
Product of tryptophan metabolism by the pineal gland
Potent effects on the control of seasonal reproduction in mammals
Synthesis and secretion subject to photoperiodic control
Tumour-inhibiting props. and role in immune system under investigation
May influence circadian rhythms in humans
生物来源
Isol. from bovine pineal glands
药理学性质
生物活性机理
Dopamine antagonist
Prolactin antagonist
描述信息
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分子图谱
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参考文献
• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 677A, (ir)
• Neville, S. et al., J. Pineal Res., 1989, 6, 73, (mutagenicity)
• Dubcovich, M.L., Adv. Pineal Res., 1991, 5, 343-349, (Melatonin, pharmacol)
• Reiter, R.J., Endocr. Rev., 1991, 12, 151, (Melatonin, rev)
• Guerrero, J.M. et al., Endocr. Rev., 1992, 18, 91, (Melatonin)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 1385, (Melatonin)
• Minneman, K.P. et al., Life Sci., 1975, 17, 1189, (rev, pharmacol)
• Amat, M. et al., Synthesis, 2001, 267-275, (Melatonin)
• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 663A
• Arendt, J., Clin. Endocrinol. (Oxford), 1988, 29, 205, (Melatonin, rev)
• Somei, M. et al., Chem. Pharm. Bull., 2001, 49, 87-96, (synth, deriv, Melatonin)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, MCB350; MFT000; MFS400
• Szmuszkovicz, J. et al., J.O.C., 1960, 25, 857, (synth, uv)
• Quarles, W.G. et al., Acta Cryst. B, 1974, 30, 99, (cryst struct)
• Marais, W. et al., Synth. Commun., 1998, 28, 3681-3691, (Melatonin)
• Mattox, S.E. et al., Biomed. Mass Spectrom., 1975, 2, 272, (synth, ms)
• Vivien-Roels, B. et al., Experientia, 1993, 49, 642, (rev, Melatonin)
• Weniger, B. et al., Planta Med., 1995, 61, 569-570, (isol, deriv)
• Adlerova, I. et al., Coll. Czech. Chem. Comm., 1960, 25, 784; CA, 54, 13095f
• Hwang, K.-J. et al., Synth. Commun., 1999, 29, 2099-2104, (Melatonin, synth, pmr)
• Somei, M. et al., Heterocycles, 2000, 53, 1725-1736, (Melatonin, synth)