物质信息

ID:449607

名称和标识
别名
ColchicineColchisolColsaloidColchiceine methyl etherArtrichine
IUPAC标准名
N-[(10S)-3,4,5,14-tetramethoxy-13-oxotricyclo[9.5.0.02,7]hexadeca-1(16),2,4,6,11,14-hexaen-10-yl]acetamide
IUPAC传统名
N-[(10S)-3,4,5,14-tetramethoxy-13-oxotricyclo[9.5.0.02,7]hexadeca-1(16),2,4,6,11,14-hexaen-10-yl]acetamide
数据登录号
CAS号
化合物性质
药理学性质
生物活性机理
Reduces phagocytosis with inflammatory
Leukocyte migration inhibitor
Phagocytosis inhibitor
Interferes with kinin formation
Response abatement
Exact mechanism unknown
产品相关信息
应用领域
Potential HIV inhibitor
Cytostatic
Antirheumatic
Immunosuppressive
生物来源
Chief alkaloid from Colchicum autumnale, many other Colchicum spp., several Merendera spp., Gloriosa superba and others (Liliaceae)
描述信息
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分子图谱
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参考文献
• Local delivery of biodegradable microparticles containing colchicine or a colchicine analogue: effects on restenosis and implications for catheter-based drug delivery.
• J.Am.Coll.Cardiol. (26, No. 6, 1549-57, 1995)