物质信息
ID:449588
名称和标识
IUPAC标准名
(6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
别名
CapsaicinCapsaieneZostrixNatural capsaicinCapsacutinMiotonAxsain
IUPAC传统名
(6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
数据登录号
CAS号
化合物性质
产品相关信息
应用领域
Used as a counterirritant and topical analgesic for some skin conditions
Irritant used for desensitisation of sensory neurones
Used as a selective probe for studying neurogenic inflammation and the role of nociceptors in human physiol
生物来源
Pungent principle of various Capsicum spp. (Solanaceae)
简要说明
Isomers
药理学性质
生物活性机理
Gastric motility inhibitor
Prevents reaccumulation of substance-P in peripheral sensory neurons
Probable mechanism: substance-P-depletor
描述信息
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分子图谱
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参考文献
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• Fusco, B.M. et al., Drugs, 1997, 53, 909-914, (rev)
• Encyclopedia of Food and Color Additives, (ed. Burdock, G.A.), CRC Press, 1997, 1374-1375
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 2, 1378C, (nmr)
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• Rangoonwala, R., Pharmazie, 1969, 24, 177, (biosynth)