物质信息
ID:449587
名称和标识
IUPAC标准名
(1S,2R,10R,11S,14R,15S)-14-ethynyl-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
别名
EthisteronePregninEthnyltestosterone17-EthynyltestosteronePregneninoloneEthynyltestosterone
IUPAC传统名
(1S,2R,10R,11S,14R,15S)-14-ethynyl-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
数据登录号
CAS号
化合物性质
药理学性质
生物活性机理
Progestogen
产品相关信息
应用领域
Orally effective progestational steroid, about one-third the activity of progesterone by subcutaneous route but more active orally
描述信息
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分子图谱
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参考文献
• Horvath, G. et al., Adv. Mass Spectrom., 1978, 7B, 1280, (ms)
• Dorfman, R.I. et al., Endocrinology (Baltimore), 1948, 42, 77, (metab)
• Ruzicka, L. et al., Helv. Chim. Acta, 1938, 21, 371, (synth)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 6284, (synonyms)
• Desaulles, P.A. et al., Acta Endocrinol., 1962, 40, 217; 1964, 47, 444, (pharmacol)
• Akhrem, A.A. et al., Izv. Akad. Nauk SSSR, Ser. Khim., 1971, 3, 601, (pmr)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 1184
• Gunatilaka, A. et al., Chem. Comm., 1978, 980, (synth)
• Inhoffen, H.H., Ber., 1939, 72, 595, (synth)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, GEK500
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 592A, (nmr)