物质信息
ID:449569
名称和标识
IUPAC标准名
(1S,2R,10R,11S,14R,15S)-15-ethyl-14-ethynyl-14-hydroxytetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
别名
Dexnorgestrel (obsol.)MirenaD -NorgestrelLevonorgestrel
IUPAC传统名
(1S,2R,10R,11S,14R,15S)-15-ethyl-14-ethynyl-14-hydroxytetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
数据登录号
CAS号
化合物性质
产品相关信息
应用领域
Tocolytic
Used in oral contraceptives
药理学性质
生物活性机理
Progestogen
描述信息
暂无数据
点击上传数据
分子图谱
暂无数据
点击上传数据
参考文献
• Delettre, J. et al., Acta Cryst. B, 1980, 36, 1505, (cryst struct)
• Cleve, G. et al., Arzneim.-Forsch., 1986, 36, 784, (mol struct)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 591C, (nmr)
• Rufer, C. et al., Annalen, 1967, 702, 141, (synth, uv)
• DeAngelis, N.J. et al., Acta Cryst. B, 1975, 31, 2040, (struct)
• Sopirak, A. et al., Anal. Profiles Drug Subst., 1975, 4, 294, (rev)
• Horvath, G. et al., Adv. Mass Spectrom., 1978, 7B, 1280, (ms)
• Baier, H. et al., Helv. Chim. Acta, 1985, 68, 1054, (synth, cd, abs config, uv, ir, pmr)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 6287; 6288
• Jones, R.C. et al., Int. J. Fertil., 1979, 24, 39, (props, enantiomers)
• Coukell, A.J. et al., Drugs, 1998, 55, 861-887, (rev)
• Michnowicz, J. et al., Org. Mass Spectrom., 1972, 6, 765, (ms)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 1190
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, NNQ500; NNQ520; NNQ525
• Rosenberger, M. et al., Helv. Chim. Acta, 1971, 54, 2857, (synth)
• Ranney, R.E., J. Toxicol. Environ. Health, 1977, 3, 139, (rev, metab)
• Smith, H. et al., J.C.S., 1964, 4472, (synth)
• Sauer, G. et al., Angew. Chem., Int. Ed., 1975, 14, 417, (synth)
• U.S. Pat., 1967, 3 338 925; CA, 68, 22142, (synth)