物质信息
ID:449534
名称和标识
IUPAC标准名
6-(5-chloropyridin-2-yl)-7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate
别名
ImovaneZopicloneZimovaneAmobanImovance
IUPAC传统名
6-(5-chloropyridin-2-yl)-7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate
数据登录号
CAS号
化合物性质
产品相关信息
应用领域
Psychosedative
Tranquilizer
Anticonvulsant
Sedative
药理学性质
生物活性机理
The mechanism of action of zopiclone is similar to benzodiazepines, with similar effects on locomotor activity and on dopamine and serotonin turnover
描述信息
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分子图谱
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参考文献
• Goa, K.L. et al., Drugs, 1986, 32, 48, (rev, pharmacol)
• Brun, J.P., Pharmacol., Biochem. Behav., 1988, 29, 831, (rev)
• Noble, S. et al., Drugs, 1998, 55, 277-302, (rev)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 622
• Jeanmart, C. et al., C. R. Hebd. Seances Acad. Sci. Ser. C, 1978, 287, 377, (synth, pharmacol)
• Schulz, M., Pharm. Ztg., 1991, 136, 26; 30, (rev)
• Fernandez, C. et al., Clin. Pharmacokinet., 1995, 29, 431, (rev, pharmacokinet)
• Borea, P.A. et al., Mol. Pharmacol., 1987, 31, 334, (struct)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, ZUA450
• Bertolasi, V. et al., J.C.S. Perkin 2, 1990, 283, (cryst struct)