物质信息
ID:449522
名称和标识
IUPAC标准名
1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
别名
TequinGatifloxacin
IUPAC传统名
1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
数据登录号
CAS号
化合物性质
药理学性质
生物活性机理
Inhibits the bacterial enzymes DNA gyrase and topoisomerase IV
产品相关信息
应用领域
Antibacterial
Antibiotic
描述信息
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分子图谱
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参考文献
• Hosaka, M. et al., Antimicrob. Agents Chemother., 1992, 36, 2108; 1996, 40, 2756, (activity, pharmacol)
• Casta~ner, J. et al., Drugs of the Future, 1993, 18, 203
• Perry, C.M. et al., Drugs, 1999, 58, 683, (rev)
• Eur. Pat., 1987, Sankyo, 241 206; CA, 110, 135095, (synth, activity)
• Wakabayashi, E. et al., Antimicrob. Agents Chemother., 1994, 38, 594, (activity)
• Dalhoff, A., Expert Opin. Invest. Drugs, 1999, 8, 123