物质信息
ID:449449
名称和标识
别名
TriclabendazoleFasinex
IUPAC标准名
5-chloro-6-(2,3-dichlorophenoxy)-2-(methylsulfanyl)-1H-1,3-benzodiazole
IUPAC传统名
5-chloro-6-(2,3-dichlorophenoxy)-2-(methylsulfanyl)-1H-1,3-benzodiazole
数据登录号
CAS号
化合物性质
产品相关信息
简要说明
Tautomers (~1:1)
应用领域
Anthelmintic (with active sulfoxide metabolite)
药理学性质
生物活性机理
Binds to beta-tubulin and prevent the polymerisation of the microtubules of which they are part
描述信息
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分子图谱
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参考文献
• Stitt, A.W. et al., Parasitol. Res., 1993, 79, 529, (pharmacol)
• Negro, A. et al., J. Chromatogr., 1992, 576, 135, (hplc)
• Ger. Pat., 1978, Ciba-Geigy, 2 815 621; CA, 90, 38919c, (synth, pharmacol)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, CFL200
• Martin, P.A. et al., Vet. Rec., 1993, 133, 300, (tox)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 55