物质信息
ID:449224
名称和标识
IUPAC标准名
2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid
别名
CiprolLipanorCiprofibrate
IUPAC传统名
2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid
数据登录号
CAS号
化合物性质
产品相关信息
应用领域
Effective in type Iia, Iib, III and IV hyperlipoproteinaemias and increases high-density lipoprotein
Hypolipidaemic agent
药理学性质
生物活性机理
Agonist of the PPARalpha receptor in muscle, liver, and other tissues
描述信息
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分子图谱
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参考文献
• Martindale, The Extra Pharmacopoeia, 31st edn., Pharmaceutical Press, 1996, 1304
• Gibson, G. et al., Peroxisomes: Biology and Importance in Toxicology and Medicine, Taylor and Francis, London, 1993, (rev)
• Chapman, M.J. et al., Atherosclerosis (Amsterdam), 1996, 124; S83, (pharmacol, use)
• Beyer, K.H. et al., Arch. Pharm. (Weinheim, Ger.), 1982, 315, 1049, (metab)
• Masnatta, L.D. et al., J. Chromatogr., B: Biomed. Appl., 1996, 687, 437, (hplc)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, CMS210
• Arnold, A. et al., J. Pharm. Sci., 1979, 68, 1557, (props)
• Fr. Pat., 1974, Sterling Drug, 2 197 586; CA, 82, 43059m, (synth, pharmacol)