物质信息
ID:449217
名称和标识
别名
ZometaZoledronic Acid
IUPAC标准名
[1-hydroxy-2-(1H-imidazol-1-yl)-1-phosphonoethyl]phosphonic acid
IUPAC传统名
[1-hydroxy-2-(1H-imidazol-1-yl)-1-phosphonoethyl]phosphonic acid
数据登录号
CAS号
化合物性质
产品相关信息
应用领域
Prevents skeletal fractures in patients with multiple myeloma and prostate cancer
药理学性质
生物活性机理
Bone resorption inhibitor
Human gamma-lambda T cells activator
Calcium regulator
描述信息
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分子图谱
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参考文献
• Berenson, J.R. et al., Cancer (Philadelphia), 2001, 91, 144-154, (pharmacol)
• Dunford, J.E. et al., J. Pharmacol. Exp. Ther., 2001, 296, 235-242, (pharmacol)
• Green, J.R. et al., J. Bone Min. Res., 1994, 9, 745, (pharmacol)
• U.S. Pat., 1990, Ciba-Geigy, 4 939 130; CA, 114, 62355a, (synth, pharmacol)
• Sorbera, L.A. et al., Drugs of the Future, 2000, 25, 259-268, (rev)
• Cheer, S.M. et al., Drugs, 2001, 61, 799-805, (rev)