物质信息
ID:449138
名称和标识
IUPAC标准名
(2Z)-but-2-enedioic acid; 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one
别名
Domperidone Maleate
IUPAC传统名
(2Z)-but-2-enedioic acid; 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one
数据登录号
CAS号
化合物性质
药理学性质
生物活性机理
Dopamine D2 antagonist
Antidopaminergic
产品相关信息
应用领域
Antiemetic drug
成盐信息
Maleate
描述信息
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分子图谱
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参考文献
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, DYB875
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 7th edn., Akademie-Verlag, 1994, 8895
• Ger. Pat., 1977, 2 632 870; CA, 87, 23274c, (synth, pharmacol)
• Emanuel, M.B. et al., Clin. Res. Rev., 1983, 3, 15; 57; 91, (revs)
• Prakash, A. et al., Drugs, 1998, 56, 429-445, (rev)
• Brogden, R.N. et al., Drugs, 1982, 24, 360, (rev, pharmacol)
• Kennis, L.E.J. et al., Drug Dev. Res., 1986, 8, 133, (synth, props)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 882