物质信息
ID:399016
名称和标识
IUPAC传统名
2-(2,4-difluorophenyl)-6-[1-(2,6-difluorophenyl)carbamoylamino]pyridine-3-carboxamide
IUPAC标准名
2-(2,4-difluorophenyl)-6-[1-(2,6-difluorophenyl)carbamoylamino]pyridine-3-carboxamide
别名
VX-7026-[(Aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamide
数据登录号
CAS号
描述信息
VX-702 is a p38 mitogen-activated protein kinase (MAPK) inhibitor. VX-702 had no effect on platelet aggregation induced by any of the p38 MAPK agonists. VX-702 has potential use in the treatment of inflammation, rheumatoid arthritis and cardiovascular dis
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参考文献
• Ding, C.: Curr. Opin. Invest. Drug, 7, 1020 (2004)
• Cohen, S. et al.: Curr. Opin. Rheumatol., 22, 330 (2004)
• Kuliopulos, A. et al.: Thromb. Haemost., 92, 1387 (2004)