物质信息
ID:398065
名称和标识
IUPAC标准名
cyclopentyl (2S)-2-[(2R,3S)-3-hydroxy-3-(hydroxycarbamoyl)-2-(2-methylpropyl)propanamido]-2-phenylacetate
IUPAC传统名
cyclopentyl (2S)-2-[(2R,3S)-3-hydroxy-3-(hydroxycarbamoyl)-2-(2-methylpropyl)propanamido]-2-phenylacetate
别名
(αS)-α-[[(2R)-2-[(1S)-1-Hydroxy-2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]amino]benzeneacetic Acid Cyclopentyl EsterTosedostatCHR 2797
数据登录号
CAS号
描述信息
CHR-2797 is a novel metalloenzyme inhibitor that is converted into a pharmacological active acid product (CHR-79888) inside cells. CHR-2797 exerts antiproliferative effects against a range of tumor cell lines in vitro and in vivo and shows selectivity fo
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参考文献
• Saveanu, L., et al.: Nat. Immunol., 6, 689 (2004)
• Proud, C., et al.: Biochem. J., 403, 217 (2004)
• Watatani, Y., et al.: Life Sci., 80, 879 (2004)
• Sato, Y., et al.: Biol. Pharm. Bull., 27, 772 (2004)