物质信息
ID:397299
名称和标识
IUPAC传统名
testolactone
别名
NSC 23759TestolactonTeslakΔ1-Testolactone1,2-DehydrotestololactoneΔ1-Dehydrotestololactone17a-Oxa-D-homo-1,4-androstadiene-3,17-dioneFludestrinΔ1-Testololactone1,2-DidehydrotestololactoneSQ 953813-Hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic Acid δ-LactoneTeolitTeslac(4aS,4bR,10aR,10bS,12aS)-3,4,4a,5,6,10a,10b,11,12,12a-decahydro-10a,12a-dimethyl-2H-phenanthro[2,1-b]pyran-2,8(4bH)-dioneD-Homo-17a-oxaandrosta-1,4-diene-3,17-dione1-DehydrotestololactoneΔ1-Testolactone
IUPAC标准名
(1R,2S,7S,10S,11R)-7,11-dimethyl-6-oxatetracyclo[8.8.0.02,7.011,16]octadeca-12,15-diene-5,14-dione
数据登录号
CAS号
描述信息
Antineoplastic; non-selective steroidal aromatase inhibitor that prevents the conversion from androgen to estrogen. Used in in the treatment of familial male precocious puberty. An effective anti-tumor agent.
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参考文献
• Holbeck, S.L. et al.: Mol. Cancer Therap., 9, 1451 (2006)
• Eugster, E. A.: Treat. Endocrinol., 3, 141 (2006)
• Dunkel, L.: Mol. Cell. Endocrinol., 254, 207 (2006)