物质信息
ID:397274
名称和标识
IUPAC传统名
terbinafine hydrochloride
IUPAC标准名
[(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)(naphthalen-1-ylmethyl)amine hydrochloride
别名
Terbinafine hydrochlorideLamisilMuzonalTerbinaBramizilTerbineN-[(2E)-6,6-Dimethyl-2-hepten-4-ynyl]-N-methyl-1-naphthalenemethanaminetrans-N-Methyl-N-(1-naphthylmethyl)-6,6-dimethylhept-2-en-4-ynyl-1-amineBramazil
数据登录号
CAS号
描述信息
An orally active, antimycotic allylamine related to Naftifine. A specfic inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis. Antifungal.
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参考文献
• Ryder, N.S., et al.: Antimicrob. Agents Chemother., 27, 252 (1984)
• Evans, E.G.V., et al.: Br. Med. J., 318, 1031 (1984)
• Petranyi, G., et al.: Science, 224, 1239 (1984)