物质信息
ID:396897
名称和标识
IUPAC标准名
3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid
IUPAC传统名
3-(4-methyl-2-{[(3Z)-2-oxo-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid
别名
3-[3-(2-Carboxyethyl)-4-methylpyrrol-2-methylidenyl]-2-indolinone2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl-1H-pyrrole-3-propanoic AcidSU 5402
数据登录号
CAS号
化合物性质
理化性质
外观
Yellow-Green Solid
溶解度
DMSO
Methanol
熔点
>222°C (dec.)
产品相关信息
质检报告
安全信息
保存条件
-20°C Freezer
MSDS下载
描述信息
A specific FGFR (fibroblast growth factor receptor) inhibitor. An intermediate for 3-(hetero)arylmethylidene-2-indolinone derivatives as modulators of protein kinase activity for use in treating cancer.
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参考文献
• Cronauer, M., et al.: Eur. Urol., 43, 309 (1998)
• Korynevska, A., et al.: Biochem. Pharmacol., 74, 1713 (1998)
• Pao, W., et al.: J. Clin. Oncol., 23, 2556 (1998)
• Li, T., et al.: Clin. Cancer R
• Panek, R., et al.: J. Pharmacol. Exp. Ther., 286, 569 (1998)