物质信息

ID:395450

(R)-Pramipexole Dihydrochloride

名称和标识
IUPAC传统名
mirapex
IUPAC标准名
(6R)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
别名
R-(+)-Pramipexole DihydrochlorideDexpramipexole Dihydrochloride(R)-4,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamine Dihydrochloride(R)-Pramipexole Dihydrochloride
数据登录号
化合物性质
理化性质
外观
White to Off-White Solid
溶解度
DMSO
Methanol
熔点
270-272°C (dec.)
安全信息
MSDS下载
保存条件
-20°C Freezer, Under Inert Atmosphere
产品相关信息
质检报告
描述信息
The opposite enantiomer of Pramipexole (P700755), a dopamine-D2-receptor agonist. Dexpramipexole is a low-molecular-weight, water-soluble, orally bioavailable, renally excreted compound with linear pharmacokinetics.
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参考文献
• Mierau, J., et al.: J. Med. Chem., 30, 494 (1987)
• Schilling, J.C., et al.: Clin. Pharmacol. Ther., 51, 541 (1987)
• Kieburtz, K., et al.: J. Am. Med. Assoc., 278, 125 (1997)