物质信息
ID:394676
名称和标识
别名
4,4'-[1,5-Pentanediylbis(oxy)]bis-benzenecarboximidamidePentamidine4,4'-Diamidino-.alpha.,.omega.-diphenoxypentaneNSC 9921MP 601205p,p'-(Pentamethylenedioxy)dibenzamidine
IUPAC标准名
4-{[5-(4-carbamimidoylphenoxy)pentyl]oxy}benzene-1-carboximidamide
IUPAC传统名
pentamidine
数据登录号
CAS号
化合物性质
理化性质
溶解度
Methanol (Sparingly)
DMSO
外观
Off-White Solid
熔点
198-200°C (dec.)
产品相关信息
质检报告
安全信息
MSDS下载
保存条件
-20°C Freezer, Under Inert Atmosphere
描述信息
Has been widely used as a drug to treat protozoal diseases, such as malaria, amoebic dysentery and trypanosomiasis. It has also been shown to be effective for both prophylaxis of pneumocystic carinii pneumonia (PCC).
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参考文献
• Debs, R.J., et al.: Antimicrob. Agents Chemother., 31, 37 (1987)
• Goa, K.L., et al.: Drugs, 33, 242 (1987)
• Hesk, D., et al.: J. Lab. Comp. Radiopharm., 28, 11, 1309 (1990)
• Walzer, P.D., et al.: Antimicrob. Agents Chemother., 32, 896 (1987)