物质信息
ID:392808
名称和标识
别名
(2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acidISP-IThermozymocidinMyriocin[2S-(2R*,3S*,4S*,6E)]-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic Acid(+)-MyriocinNSC 177379(2S,3R,4R)-(E)-2-Amino-3,4-dihydroxy-2-hydroxymethyl-14-oxoeicos-6-enoic Acid
IUPAC标准名
(3R,4R,6E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid
IUPAC传统名
(3R,4R,6E)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxoicos-6-enoic acid
数据登录号
CAS号
描述信息
Myriocin is a atypical amino acid and an antibiotic with potent immunosuppressant activity. Studies suggest that the immunosuppressant activity in the cytotoxic T-cell line CTTL-2 is due to apoptosis induction. Myriocin very potent inhibitor of serine pal
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参考文献
• Hidari, K.I.P.J. et al.: J. Biol. Chem., 271, 14636 (1995)
• Miyake, Y., et al.: Biochem. Biophys. Res. Commun., 211, 396 (1995)
• Nakamura, S. et al.: J. Biol. Chem., 271, 1255 (1995)
• De Zélicourt, A. et al.: Planta 230, 1047 (1995)