物质信息
ID:390255
名称和标识
IUPAC标准名
1-methyl-1H-imidazole-2-thiol
IUPAC传统名
2-mercapto-1-methylimidazole
别名
MercazolylThiamazoleBasolanMercazoleTapazole1,3-Dihydro-1-methyl-2H-imidazole-2-thione2-Mercapto-1-methylimidazoleMetazolo1-Methylimidazole-2-thiolMethimazole
数据登录号
CAS号
描述信息
Methimazole is a thiourea antithyroid agent that prevents iodine organification, thus inhibiting the synthesis of thyroxine. Antihyperthyroid.
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参考文献
• Sitar, D.S., et al.: J. Pharmacol. Exp. Ther., 184, 432 (1973)
• Cooper, D.S., et al.: N. Engl. J. Med., 311, 1353 (1973)
• Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 8, 351 (1973)
• Atterwill, C.K., et al.: Food Chem. Toxicol., 29, 355 (1973)