物质信息
ID:388447
名称和标识
IUPAC标准名
(6S,9aS)-N-benzyl-6-[(4-hydroxyphenyl)methyl]-8-(naphthalen-1-ylmethyl)-4,7-dioxo-octahydro-1H-pyrimido[1,2-a]piperazine-1-carboxamide
IUPAC传统名
(6S,9aS)-N-benzyl-6-[(4-hydroxyphenyl)methyl]-8-(naphthalen-1-ylmethyl)-4,7-dioxo-tetrahydro-2H-pyrimido[1,2-a]piperazine-1-carboxamide
别名
(6S,9aS)-Hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide(S,S)-ICG 001
数据登录号
CAS号
描述信息
(S,S)-ICG 001 is a β-turn peptidomimetic molecule inhibitor of β-catenin-Tcf-mediated transcription.
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参考文献
• McMillan, M., et al.: Drug Discov. Today, 10, 1467 (2005)
• Brantjes, H., et al.: Biol. Chem., 383, 255 (2005)
• Nusse, R., et al.: Cell Res., 15, 28 (2005)
• Eguchi, M., et al.: Med. Chem., 1, 467 (2005)