物质信息
ID:387569
(R)-3-Hydroxymethylmorpholine-4-carboxylic Acid tert-Butyl Ester
名称和标识
IUPAC标准名
tert-butyl (3R)-3-(hydroxymethyl)morpholine-4-carboxylate
IUPAC传统名
tert-butyl (3R)-3-(hydroxymethyl)morpholine-4-carboxylate
别名
(R)-3-Hydroxymethylmorpholine-4-carboxylic Acid tert-Butyl Ester(3R)-3-(Hydroxymethyl)-4-morpholinecarboxylic Acid 1,1-Dimethylethyl Estertert-Butyl (3R)-3-(Hydroxymethyl)morpholine-4-carboxylate(R)-N-Boc-3-Hydroxymethylmorpholine
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CAS号
描述信息
An intermediate of BMS-599626, a selective and orally efficacious inhibitor of human epidermal growth factor receptor 1 and 2 kinases.
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参考文献
• Hunt, J., et al.: J. Med .Chem., 47, 4054 (1999)
• Fink, B., et al.: Bioorg. Med. Chem. Lett., 15, 4774 (1999)
• Xia, W., et al.: Clin. Cancer Res., 5, 4164 (1999)
• Baselga, J., et al.: J. Clin. Oncol., 23, 2445 (1999)