物质信息
ID:385892
名称和标识
IUPAC标准名
(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-dodecahydro-1H-naphtho[2,1-b]pyran-5-yl acetate
别名
ForskolinColeonolColforsin(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-Naphtho[2,1-b]pyran-1-oneNSC 357088(-)-ForskolinForsLeanL 75-1362BHL 362
IUPAC传统名
forskolin
数据登录号
CAS号
描述信息
Forskolin is a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP.
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参考文献
• Lindner, E., et al.: Arzneim.-Forsch., 28, 284 (1984)
• Lai, S., et al.: Eur. J. Clin. Microbiol. Infect. Dis., 24, 5831 (1984)
• Hoever, G., et al.: J. Med. Chem., 48, 1256 (1984)