物质信息
ID:383900
名称和标识
IUPAC传统名
3,3'-diindolylmethane
IUPAC标准名
3-(1H-indol-3-ylmethyl)-1H-indole
别名
3,3'-DiindolylmethaneDIMBis(1H-indol-3-yl)methane 3,3'-Methylenediindole3,3'-Methylenebis-1H-indole3,3'-DiindolylmethaneHB 236Arundine3,3'-BisindolylmethaneBis(3-indolyl)methane
数据登录号
CAS号
描述信息
3,3'-Diindolylmethane is an activator of Chk2 that causes G2/M cell cycle arrest in various cancer cell lines. 3,3'-Diindolylmethane is an antiproliferative and inducer of apoptosis; promotes proteasomal degradation of Cdc25C and Cdk1. Inhibits phosphoryl
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参考文献
• Kandala, et al.: Mol.Pharmacol., 78, 297 (2010)
• Kandala, et al.: J. Pharmacol. Exp. Ther., 341 24 (2010)