物质信息
ID:381934
名称和标识
IUPAC传统名
clarinex
IUPAC标准名
13-chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene
别名
DesloratadineDescarboethoxyloratadineClarinexNeoclaritynSch 341178-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridineAzomyrAeriusAllexOpulisNSC 675447
数据登录号
CAS号
化合物性质
产品相关信息
质检报告
理化性质
溶解度
Hexane
Chloroform
Ethyl Acetate
熔点
150-151°C
外观
Off-White to Beige Solid
安全信息
MSDS下载
保存条件
-20°C Freezer
描述信息
Nonsedating-type histamine H1-receptor antagonist. An active metabolite of Loratadine. Also inhibits generation and release of inflammatory mediators from basophils and mast cells.An impurity arising in the synthesis of Rupatadine (R701650).
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参考文献
• Salmun, L.M., et al.: Clin. Ther., 22, 613 (2000)
• Kreutner, W., et al.: Arzneimittel-Forsch., 50, 345 (2000)
• Agrawal, D.K., et al.: Expert Opin. Invest. Drugs, 10, 547 (2000)