物质信息

ID:381566

5'-Deoxy-5'-(methylthio)adenosine

名称和标识
IUPAC标准名
(2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-[(methylsulfanyl)methyl]oxolane-3,4-diol
IUPAC传统名
methylthioadenosine
别名
5'-Deoxy-5'-(methylthio)adenosine5'-(Methylthio)-5'-deoxyadenosine5'-(Methylthio)adenosineNSC 335422Vitamin L21-(6-Amino-9H-purin-9-yl)-1-deoxy-5-S-methyl-5-thio-β-D-ribofuranose5'-S-Methyl-5'-thioadenosine5'-Deoxy(methylthio)adenosine5'-S-Methylthioadenosine
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描述信息
5′-Deoxy-5′-(methylthio)adenosine (Methylthioadenosine) may be used as a substrate to study the specificity and kinetics of 5′-methylthioadenosinephosphorylase (MTAP) (EC2.4.2.28), a tumor suppressor gene expressed enzyme that supports the S-adenosylmethi
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参考文献
• Hartmann, S., et al.: Clin. Chem., 52, 1127 (1969)
• Olopade, O., et al.: Cancer Res., 53, 2410 (1969)
• Penner, N., et al.: J. Pharm. Biomed. Anal., 52, 534 (1969)
• Pegg, A., et al.: Biochem. J., 115, 241 (1969)