物质信息
ID:380585
名称和标识
IUPAC标准名
4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin-4-yl)phenyl]-2,5-dihydropyrimidin-2-imine
IUPAC传统名
4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin-4-yl)phenyl]-5H-pyrimidin-2-imine
别名
CYC-1165-[2,5-Dihydro-2-[[4-(4-morpholinyl)phenyl]imino]-4-pyrimidinyl]-4-methyl-2-thiazolamine
数据登录号
CAS号
描述信息
An Aurora kinase inhibitor, used to treat patients with advanced solid tumors.
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参考文献
• Verdonk, M., et al.: J. Med. Chem., 48, 6504 (2000)
• Carlson, H., et al.: Mol. Pharmacol., 57, 213 (2000)
• Hou, T., et al.: Curr. Pharm. Des., 10, 1011 (2000)