物质信息

ID:380245

名称和标识
别名
ClotiazepamTrecalmo5-(o-Chlorophenyl)-7-ethyl-1-methyl-1,2-dihydro-3H-thieno[2,3-e][1,4]diazepin-2-oneY 60475-(o-Chlorophenyl)-7-ethyl-1,3-dihydro-1-methyl-2H-thieno[2,3-e]-1,4-diazepin-2-oneRizenTienorRizeVeratranClotiazepamClozan1-Methyl-5-o-chlorophenyl-7-ethyl-1,2-dihydro-3H-thieno[2,3-e][1,4]diazepin-2-one
IUPAC标准名
5-(2-chlorophenyl)-7-ethyl-1-methyl-1H,2H,3H-thieno[2,3-e][1,4]diazepin-2-one
IUPAC传统名
rize
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描述信息
A thienodiazepine derivative that possesses anxiolytic, skeletal muscle relaxant anticonvulsant, sedative properties as well as contributing to siginificant increase stage 2 NREM sleep. It binds to benzodiazepine site of the GABAA receptor where it acts a
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参考文献
• Yakushiji, T. et al.: Br. J. Pharmacol., 98, 735 (2008)
• Mandrioli, R. et al.: Curr.Drug Metab., 8, 827 (2008)
• Nakazawa, Y. et al.: Psychopharmacol., 44, 165 (2008)