物质信息
ID:378735
名称和标识
IUPAC传统名
caspofungin
别名
1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-(threo-3-hydroxy-L-ornithine)pneumocandin B0 DiacetateMK 0991L 7438731-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]pneumocandin B0 DiacetateCaspofungin AcetateCaspofungin DiacetateCancidasL 743872
IUPAC标准名
N-[(3S,6S,9S,11R,15S,18S,20R,21S,24S,25S)-3-[(1R)-3-amino-1-hydroxypropyl]-21-[(2-aminoethyl)amino]-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-11,20,25-trihydroxy-15-[(1R)-1-hydroxyethyl]-2,5,8,14,17,23-hexaoxo-1,4,7,13,16,22-hexaazatricyclo[22.3.0.09,13]heptacosan-18-yl]-10,12-dimethyltetradecanamide
数据登录号
CAS号
化合物性质
理化性质
熔点
204-206°C
溶解度
Methanol
外观
White Solid
安全信息
MSDS下载
保存条件
-20°C Freezer, Under Inert Atmosphere
产品相关信息
质检报告
描述信息
An echinocandin that inhibits the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall. An antifungal drug used in the treatment of invasive fungal infections.
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参考文献
• Hoang, A.: Am. J. Health-Sys. Pharm., 58, 1206 (2004)
• Sandhu, P. et al.: Antimicrob. Agents Chemorther., 48, 1272 (2004)
• Bertsche, T. et al.: Pharamaz. Zeit., 148, 34 (2004)