物质信息
ID:378690
名称和标识
IUPAC标准名
3,3-dimethyl-1-[(1r,4r)-4-{2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl}cyclohexyl]urea
别名
CariprazineN'-[trans-4-[2-[4-(2,3-Dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-N,N-dimethylureaRGH 188
IUPAC传统名
cariprazine
数据登录号
CAS号
描述信息
Cariprazine is an orally active D2/D3 dopamine receptor antagonist. Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression
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参考文献
• Gruender, G. et al.: Curr. Opin. Invest. Drugs, 11, 823 (2010): Seneca, N. et al.: Psychopharmacology, 218, 579 (2011)
• Kiss, B. et al.: J. Pharmacol. Exp. Therap., 333, 328 (2011)