物质信息
ID:378405
名称和标识
别名
BlopressCandesartan cilexetilAtacand2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid 1-[[(Cyclohexyloxy)carbonyl]oxy]ethyl EsterTCV 116
IUPAC标准名
1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 2-ethoxy-1-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-1,3-benzodiazole-7-carboxylate
IUPAC传统名
1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 2-ethoxy-3-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1,3-benzodiazole-4-carboxylate
数据登录号
CAS号
描述信息
Ester prodrug; hydrolized in vivo to the active carboxylic acid. Used in treatment of congestive heart failure. Antihypertensive.
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参考文献
• Ogihara, T., et al.: Clin. Ther., 16, 74 (1994)
• Shibouta, Y., et al.: J. Pharmacol. Exp. Ther., 266, 114 (1993)