物质信息
ID:374567
名称和标识
别名
AnacetrapibMK 0859(4S,5R)-5-[3,5-Bis(trifluoromethyl)phenyl]-3-[[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methyl]-4-methyl-1,3-oxazolidin-2-one(4S,5R)-5-[3,5-Bis(trifluoromethyl)phenyl]-3-[[4'-fluoro-2'-methoxy-5'-(1-methylethyl)-4-(trifluoromethyl)[1,1'-biphenyl]-2-yl]methyl]-4-methyl-2-oxazolidinone
IUPAC传统名
anacetrapib
IUPAC标准名
(4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-({2-[4-fluoro-2-methoxy-5-(propan-2-yl)phenyl]-5-(trifluoromethyl)phenyl}methyl)-4-methyl-1,3-oxazolidin-2-one
数据登录号
CAS号
描述信息
An orally active and potent cholesterol ester transfer protein (CETP) inhibitor for the treatment of atherosclerosis, in particular dyslipidemia.
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参考文献
• Masson, D.: Curr. Opin. Invest. Drugs, 10, 980 (2009)
• Krishna, R. et al.: Br. J. Clin. Pharmacol., 67, 520 (2009)
• Vergeer, M. et al.: Nat. Clin. Pract. Cardiovasc. Med., 5, 302 (2009)